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B. Ramya Kuber ¹, C. Veeresham ², K. Asres ³

Affiliations
1 Department of Pharmaceutical Sciences, Sri Padmavathi Mahila University, Tirupathi, A.P., IN
2 Kakatiya University, Warangal, A.P. - 506009, IN
3 School of Pharmacy, Addis Ababa, ET

Abstract

Microscopic, physiochemical and pharmaceutical parameters of herbal formulations of Withania somnifera were evaluated. Both qualitative and quantitative phytochemical analyses were conducted on the extracts prepared from these formulations. The anti-stress and locomotor activities of these formulations were also investigated. Results from the study showed that the ischolar_main powder, powdered preparation and capsules contain withanolides including withaferin A as active constituents. Microscopic examination of the capsule formulation, which was labeled as dry extracts of W. somnifera, revealed that it contains phloem fibers, starch and parenchyma cells indicating that the capsules were not prepared from only genuine extracts of W. somnifera.

Keywords

Withania somnifera, Herbal Formulations, Anti-Stress Activity, Withanolides, HPLC Analysis.

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M. Swapna Reddy ¹, B. Ramya Kuber ²

Affiliations
1 Vaagdevi Pharmacy College, Bollikunta, Warangal, IN
2 Sri Padmavathi Mahila Visvavidyalayam, Tirupathi, IN

Abstract

Present study was aimed on evaluation of the antibacterial activity of leaves of Mimusops elengi and Moringa oleifera against Bacillus subtilis and Escherichia coli respectively using different solvents like, hexane, petroleum ether, chloroform, methanol and water. Mimusops elengi is an evergreen tree and have many traditional uses and Moringa oleifera is highly nutritious plant, have high nutritive value when compared to the daily used food products like milk, banana, eggs etc. these plants have many medicinal uses like analgesic, ant tubercular activity, antipyretic, anti-inflammatory etc., Cylindrical plate method was used to assess the effect of the extracts on B. subtilis and E. coli at 25 μl, 35 μl and 50 μl concentration. Among the extracts obtained from five solvents, only chloroform , methanol and aqueous extracts showed the inhibition compared with a standard antibiotic Streptomycin. In solvent extract of Mimusops elengi at 25 μl to 50 μl concentration, methanol recorded a maximum inhibition of 25.7mm and 31.3mm against B. subtilis. In solvent extract of Moringa oleifera at 25 μl to 50 μl concentration, aqueous extract recorded maximum inhibition of 5mm against E. coli.

Keywords

Antibacterial, Moringa oleifera and Mimusops elengi.

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